It has been three months since the incident at Yokohama. Things have been settling down at Cafe Nowhere. Murasaki and Hajime have teamed up and started investigating again. After an unforeseen reunion, Art holds Nice at gunpoint. What are his real intentions? What will become of the connection between Art and Hamatora? (Source: Crunchyroll)

A reunion that was supposed to spell the arrival of peaceful times is quickly shattered when Subaru Natsuki and Emilia return to Irlam village. Witnessing the devastation left behind by the calamities known as Sin Archbishops, Subaru sinks into the depths of despair as his ability to redo proves futile. As the group makes their way to the Sanctuary in search of answers, Subaru has an unexpected encounter with the Witch of Greed—Echidna. Subjected to her untamed rhythm, he is forced to dive into the spirals of the past and future. At the same time, several mysterious threats set their sights on the Sanctuary, heralding a horrific fate for the hapless people trapped within. Everlasting contracts, past sins, and unrequited love will clash and submerge into a river of blood in the second season of Re:Zero kara Hajimeru Isekai Seikatsu. Pushed to the brink of hopelessness, how long will Subaru's resolve to save his loved ones last? [Written by MAL Rewrite]

After the battle with the Witch Cult, Subaru travels back to Crusch's manor with Emilia, when he discovers, to his horror, that everyone has forgotten Rem. Earlier, she and Crusch were ambushed by the Sin Archbishops of Gluttony, Lye Batenkaitos, and Greed, Regulus Corneus. Although they fought fiercely, both ended up having their existences eaten by Lye. This caused Rem to fall into a coma, with noone but Subaru remembering her, and Crusch lost her memories. After learning what happened, a devastated Subaru commits suicide in hopes of going back in time to before the ambush to prevent it. However, it fails as he returns to after the ambush had already occurred. Subaru later attends a meeting with Emilia, the amnesiac Crusch, Felis and Wilhelm. After a heated discussion, they decide to continue their alliance. After the meeting, Emilia comforts Subaru as he grieves for Rem.

The continent of Atlatan once again finds itself devoured by the flames of war after a horrific event known as the Great Hall Tragedy. What was supposed to be a joyful occasion that would establish peace between the Fantasia Union and the Factory Alliance, the marriage of Sir Alexis Douse and Lady Marrine Kreische, was instead a tragedy. As the bride and groom walked down the aisle, the ceremony was suddenly interrupted by a powerful convergence of "Chaos," a dark energy from another dimension that corrupts the land and brings forth monsters and demons into the world. From within that energy appeared the Demon Lord of Diabolos, an evil being who instantly murdered the archdukes of both factions, shattering any hope for peace between them. Having failed to prevent this disaster, Siluca Meletes, an Alliance mage, is traveling through the Chaos-infested countryside to study under a master magician. When she is intercepted by a group of soldiers working with the Federation, Siluca is rescued by Theo Cornaro, a young warrior carrying a mysterious "Crest," a magical symbol that gives its wielder the ability to banish Chaos. Bearing no allegiance to a specific domain, Theo hopes to attain the rank of Lord so that he can liberate his home town of Sistina from its tyrannical ruler and the Chaos spreading within it. Impressed by his noble goal, Siluca enters into a magical contract with Theo, and the two embark on a journey to restore balance to their war-torn land. [Written by MAL Rewrite]