Sometime in the distant future, mankind is forced to live in domed cities while the rest of the world is left to recover from years of environmental hardships. In the Siberian Dome-polis, professional gamer Gainer Sanga and mercenary Gain Bijou commandeer an Overman and lead a mass exodus out of the city.

In 2059, five decades after the Space War I conflict seen in the first Macross story. Macross Frontier, the 25th New Macross Class super-long-distance colonization fleet, is journeying through the galaxy to a new paradise to call home. However, it is locked in a state of war with a strange enemy called Vajra. Macross FB7 is the 30th anniversary work of the Macross franchise.

In the year 2010 AD, Hyper Hurricanes born concurrently all over the world caused severe damage. Five billion people lost their lives, decreasing the world's population to 3 billion. Existing economies and military were wiped out. Countries were frozen under solid ice, plains sank beneath seas, the world was changed dramatically. Human civilization enters a chaotic era. Poverty flourished outside of these economic zones and slums were widespread. The ruling class called themselves Logos and maintained their position by force of arms. They call the poor Revenus, who are exiled to live outside the special economic areas. Time has passed since then. Katsuragi Jo and Tsurasawa Jin, escape from Phantom, a force organized to watch Revenus and to suppress renegade elements of the Logos, taking with them a mysterious girl, Nobuto Sana. There are many who are interested in her, all with their own reasons.

In a peaceful, disarmed world where small robots are utilized as housekeepers, villains act with huge robots instead of weapons. Dr. Keewee converts Michael’s robot into a transformable one in order to teach them a lesson. This is the birth of Galatt, the town hero.