Ayakashi are strange, supernatural creatures invisible to the majority of people. Though most are harmless, some ayakashi attack humans to devour their life force. Exorcist ninjas are tasked with protecting people from these spiteful spirits. Matsuri Kazamaki is a young exorcist ninja born to a prestigious clan. His childhood friend, Suzu Kanade, is an ayakashi medium—an individual with immense vitality that attracts ayakashi. Matsuri deems all ayakashi threatening and wishes to keep Suzu as far from them as possible, but this clashes with her desire to remain close to them. One day, the pair encounters Shirogane, the "King of Ayakashi," who is hellbent on consuming Suzu. As she is about to be eaten, Matsuri comes to the rescue and manages to seal the ayakashi's powers—but not before Shirogane takes revenge by turning him into a girl! Until he finds a way to transform back, Matsuri must adjust to his new, peculiar lifestyle while fighting against hostile ayakashi. Moreover, Suzu is now conflicted about her feelings toward Matsuri—further plunging their relationship into a state of ambiguity.

Dwelling in the small outskirts of a peaceful town, Lawrence works as a local pastor for the townsfolk. When in need, he is responsible for guiding people to the church to visit the "Saint"—a symbol of good morals who heeds each parishioner's struggles and grants them sincere advice. Cecilia, a kind young girl, is tasked to fulfill this role; however, this tiresome job quickly exhausts her. That, paired with her hidden somnolent nature, often causes her to laze around the church. This leaves Lawrence to care for the church all by himself. While Cecilia sleeps in anticipation for her next visitor, Lawrence caters to her needs alongside performing the church's numerous responsibilities. Slowly but surely, they begin to form a comfortable and trusting friendship with one another. Lawrence accepting Cecilia's lax nature elates her while she grows accustomed to Lawrence's overly-doting nature. However, as the adoring and absent-minded saint's feelings for the dense and overly protective pastor progress past friendship, how will he respond?

Located at the end of the world, the Kingdom of Ozmargo is inhabited by beasts of all shapes and forms, ruled by a fearsome nameless king. After a hundred-year war between Ozmargo and the neighboring human kingdom ended, a peace treaty was signed: every year, a sacrifice must be sent to be devoured by the king on the night of revelation. Sariphi is the 99th and latest human sacrifice. Although frail-looking, she neither fears the king nor has a family or home to return to should she manage to escape from her impending demise. Intrigued by the audacious girl, the king lets Sariphi roam around the palace despite the disapproval of his advisor, Anubis. Little by little, the king and Sariphi begin to warm up to each other, but the night of revelation is fast approaching. Unbeknownst to them, the fateful day unleashes a series of events that will change the course of destiny of not only Sariphi and the king but also of their respective worlds.

Sequel to Hataraku Maou-sama!!. Lucifer and company face new challenges, form new alliances and...now there's a baby! Your favorite otherwordly crew returns in this continuation.