In the 21st century, mankind lives on two worlds. Following the collision of an ice asteroid, massive terraforming has made Venus a planet now capable of supporting life. Colonists from Earth tamed the hostile world and have thrived for four generations. But they also brought the darker side of humanity. Venus is about to get hostile again. Hiro Seno, a hotshot motorcycle jockey, witnesses the first strike against his country Aphrodia, by the rival nation of Ishtar. Huge battletanks and warplanes quickly lay waste to the city. The Aphrodian army is quick to mobilize and retaliate... and despite his opposition to warfare, Hiro finds himself fighting for his life on the front lines.

A quiet, polite, lonely immortal esper about which little is known, he is called "Locke the Superman", but often denies being so. It is not known where or when he was born, and if asked, Locke will say he does not remember. It is entirely possible this is true. However, when asked by Cornelia Prim in "Millennium of the Witch" which star he was from, Locke replied "Toa." He has appeared at various times throughout the history of the galaxy, either as a direct influence, an indirect influence, or a simple observer. Using his esper abilities, Locke can learn and do most things more quickly than a normal human. His power also allows him to remain eternally young, or even turn himself into a child again to be adopted by kind-hearted families. It is speculated he remains youthful as an excuse not to take responsibility for whatever cause he is approached for, since no one expects youths to have such responsibilities.

Three years after the defeat of Gargoyle and Neo-Atlantis, a new threat has surfaced bent on bringing the world under his control. Geiger, using advanced robot technology, is attempting to begin a world war, and take control of the devistated world after the destruction has stopped. Once again, Nadia and Jean must fight to save the world, only this time from itself.

Agerna is a planet rich in Vizorium, the one mineral necessary to space travel. So when a series of mysterious attacks on mining operations has the governments of the world pointing fingers and blaming each other, the World Welfare & Works Association naturally sends in their top agents to investigate. But are the lovely angels up to the task of stopping a mad scientist bent on taking a long dormant alien race to its final evolutionary form? Throw in a thief who's hunting a bottle of World War II-vintage wine and it's a safe bet that nobody on the planet is safe. It's more chaos, more mayhem and even more destruction than ever before as the Dirty Pair take on their wildest case yet!