Hasukawa Kazuya is in a terrible bind. His brother's new wife is also the woman that Kazuya secretly loves. Determined to avoid them both, Kazuya leaves home to live in the student dorm called Greenwood. There, he hopes to find peace of mind. Unfortunately for Kazuya, stability and peace are the last things one might find at Greenwood - home of the weirdest characters on campus.

Based on the manga Blame! by Nihei Tsutomu, serialised in Monthly Afternoon. In a city that is said to have thousands of levels, making it impossible to tell the sky from the ground, the mysterious Killy wanders the bizarre and foreboding levels of this mega-structure, where the boundaries between machine and living organism have been obscured.

At the end of the calendar 2020, the continent of Stern, which has reached the end of civilization due to the exhaustion of magic elements, ushered in the destruction of the continent under the void storm. Ye Xuan, the last god of law in the mainland, unexpectedly awakened in the era of the prosperous magic civilization three thousand years ago and became an ordinary student at the Sith Magic Academy on the border of the Kingdom of Orlando in the northwest of the mainland. In order to save the mainland and prevent the end from coming, Ye Xuan began to explore the mystery of the dark turmoil that led to the depletion of magical elements in the mainland three thousand years ago, to prevent the mainland crisis.

A virtual world was created by the present-day network called the "Digital World." The "Digital Monster," which is a digital life object, was born, and the host computer Yggdrasil managed the different Digital World areas. However, it developed the X Program of fear to eliminate all Digimon in the old world and develop a new Digital World for only certain Digimon... Now, the greatest crisis ever approaches the Digital World. The X-Digimon, a new type of Digital Monster, is hunted by the Royal Knights who protect the Digital Worlds. Their master, the network overseer Yggdrasil, seeks to set in motion Project Ark to renew the Digital Worlds and create new Digimon, but at the cost of all other digital life. This new X-Digimon will seek out the answers to its own existence as it tries to protect the life of all Digimon, and in the process it will change the Digital Worlds forever.