Saya Otonashi is a seemingly ordinary girl living a mundane life with her adoptive family in Okinawa City. In fact, her only peculiarities are suffering from anemia and being unable to remember any of her life beyond the previous year. However, Saya's forgotten past quickly comes back to haunt her—one night, she is attacked at school by a creature that feeds on human blood. Just when all hope seems lost, a mysterious man named Haji appears and fends off the creature temporarily. But when her rescuer forces her to drink his blood, Saya suddenly enters a trance and slays the monster with ease, using her own blood as a catalyst. Saya then learns of an organization named Red Shield, founded for the sole purpose of defeating the hellish beasts. Now Saya and Haji must work together with Red Shield to fight these fearsome monsters and unlock the secrets to the girl's past.

A technological hell masquerading as paradise, Tsukimihara Academy is an artificial high school that serves as the setting for the next Holy Grail War. Created by the Moon Cell computer, the school is inhabited by Earth-projected souls who have even the slightest aptitude for being a "Master." Of these 256 souls, 128 will be chosen for the main tournament and granted a Servant. With all of the Masters selected, the Academy activates a purge, targeting the remaining lifeforms for elimination. Awakening in a pool of his own blood, Hakuno Kishinami refuses to die. Fueled by unknown feelings of hatred, he vows to fight for survival. As he struggles to escape from a relentless pursuer, he finds a crimson blade plunged into the ground; and by pulling it out, Hakuno summons his own Servant, Saber, who instantly destroys his pursuer in a flurry of rose petals. With his newfound power, Hakuno must now begin his journey to Moon Cell's core, the Angelica Cage. There, he will unveil the reason for this artificial world and the secrets of his own blood-soaked past. [Written by MAL Rewrite]

Maintaining a delicate balance of power, the kingdoms of Amoria, Ishilfen, and Vanrodis rule over the continent of Kuna'anh. Even the slightest hint of trouble in one country could spark a continent-wide war. However, their one common fear is the evil dragon Daganzord, whose only meaning of existence is to devour and destroy all life. Ten years ago, a group of mages worked together in an effort to seal away the malevolent beast. But the ritual—later known as the "Balbagoa Tragedy"—was a failure, and many lost their lives. Though his parents died in this tragedy, Hiiro was saved by the swordsman Giruu. Under the latter's tutelage, Hiiro learned swordsmanship with the sole purpose of seeking revenge. Now a budding master himself, he sets out in search of Daganzord in order to realize his long-awaited vengeance, or to be consumed by the dragon and meet the same fate as his parents. [Written by MAL Rewrite]

After escaping a bus hijacking with the help of masked superhero Strange Juice, Yuuta Iridatsu finds his soul separated from his body and in the care of a perverse cat spirit, Chiranosuke. As a spirit, Yuuta wanders around his residence, the Korai House, aiming to regain his body and observe the other residents: Meika Daihatsu, a genius inventor; Mikatan Narugino, a cheerful idol; Ito Hikiotani, a shut-in NEET; and Rabura Chichibu, a spiritual medium. After catching a glimpse of Narugino's undergarments, Chiranosuke reveals to Yuuta that he becomes exponentially stronger upon seeing panties. However, if he sees another pair while he is still a spirit, his power will cause an asteroid to crash into the earth, ending the world and killing his friends. Punch Line follows Yuuta as he unravels the mysteries surrounding Korai House, its residents, and a villainous organization attempting to end the world. Will Yuuta be able to save everyone, or will the ever-present threat of panties result in their doom? [Written by MAL Rewrite]