"Mine has been a life of much shame."

Tokyo, 2036 (Showa year 111): a revolution in medical treatment has conquered death...
By means of internal nanomachines and the "S.H.E.L.L." system whose network controls them, human beings suffer no diseases, require no treatment for injuries, and are guaranteed a 120-year lifespan, free from illness. Yet this consummate social system warps the Japanese nation in a host of ways: unresolved economic disparities, ethical decadence resulting from deathlessness, grave environmental pollution, and the "Human Lost" phenomenon, in which people themselves, disconnected from the S.H.E.L.L. network, become malformed. Japan teeters wildly between two potential futures: civilization's restoration or its destruction.

Atmospheric pollution suffuses "Route 16" in the Outside—the area outside the Route 16 beltway. Youzou Oba, who lives an idle, drug-saturated life, joins Masao Horiki, a mysterious man who associates with the drag-racing gangs, on an incursion Inside—the area within the Route 7 loop where the privileged class lives—only to be embroiled in a violent struggle. When he encounters a malformed sufferer of the Human Lost phenomenon, a "Lost," Youzou's life is saved by Yoshiko Hiiragi, a girl of mysterious abilities who belongs to the anti-Lost agency H.I.L.A.M., and he discovers that he himself also possesses extraordinary powers...

Degradation and death. Life and hope. Buffeted by fate, a man tears himself apart and cries out. Rage. Sorrow. Pathos. Consumed by despair and bitter tears, Youzou Oba is himself transformed into a demon. A human lost... or a human who can find himself? 

(Source: Official Site)

Luo Zheng, who is now a menial slave, used to be a young master of a big family. Owing to the decline of his family, his sister is imprisoned by a strong force, and he has no choice but to be at others' service. However, every cloud has a silver lining. The ancient book left by his father actually conceals a magical spell that can change a human into an instrument! What is the mysterious power behind this? This is contest with fate.

The story centers on Mizutani Masayuki, an ordinary high school boy. His classmate Shimizu Sayaka lives in his home as a zealously intrusive maid, leading to uncomfortably erotic situations.

The story centers around Amaya, Iwasawa, and Uehara—three "annoying, spirited high school girls with zero motivation"—and their classmates. Their daily life is "what happens when there is nothing happening." (Source: ANN)