Loosely based on the novel Romance of the Three Kingdoms, modern day Japan sees a similar struggle for power between different rival schools with the three strongest being; Kyosho Academy led by Sousou Moutoku, Nanyo Academy by Sonsaku Hakufu and Ryuubi Gentoku from Seito High School. Together these three tousei, each with their own mangatama, fight for the honor of becoming ikkitousen and fulfilling their fated destiny through battle and conquest. (Source: ANN)

Fuguno Matsuo has never had a girlfriend all his 24 years in life and what makes things worse is that a fortune teller predicted that he never will. However, when he laid his eye on Nagisa-sensei he fell in-love right away and began earnestly wooing her. Along comes Hamaoka, a co-worker who is smitten with Fuguno, and a love-triangle ensues.

Kouta has girl troubles of the supernatural sort. For some reason, he keeps attracting the attention (and affections) of animal spirits! Having spent most of his life in the country, Kouta is understandably nervous when he moves in with his grandma to attend a high school in the big city. He hoped to make a good impression, but having Chizuru, a beautiful fox spirit, hanging off his arm didn't seem to be the sort of image he wanted to have. She's not alone in her love for Kouta, either. Nozomu, a wolf spirit, as well as other youkai have their sights set on the hapless country boy.

Hayato Izumi is running for student council president. He's studious, responsible, down to earth...and completely outmatched by his rival, Ui Wakana. Ui wins in a landslide after promising comprehensive sex education, free condoms, and other exciting reforms. Bloodied but not discouraged, Hayato licks his wounds and settles for vice president. Then Ui moves in with him. As it turns out, their parents made a drunken promise decades ago that their children would one day marry. Ui and Hayato must now balance school life with matrimony, keeping their relationship secret from a prudish student body and learning to live with each other. Can they keep the student council in line and find happiness together? Find out in Okusama ga Seitokaichou!