It's Nozomi's birthday, but it is disturbed by Bunbee chasing after a girl from another world, Chocola. When Pretty Cure rescue her, she thanks them by taking them to her country, Dessert Kingdom. In this cockaigne with rivers of juice and candy growing on trees, they feel very comfortable. But then they meet the evil Mushiban and his two subordinates Dry and Bitter. They want to take over the kingdom and change Pretty Cure into sweets. In order to save not only Nozomi's Birthday but also the whole Dessert Kingdom, Pretty Cure have to fight their way against Dry and Bitter and also against their own friend: Coco, who is being brainwashed by Mushiban.

Sickly but optimistic middle school student Nodoka Hanadera has just moved to Sukoyaka City, a place famous for its healthy atmosphere. She immediately befriends two of her classmates: the gentle but athletic Chiyu Sawaizumi, whose family runs a hot spring inn, and the bubbly and fashionable daughter of a vet, Hinata Hiramitsu.

Soon after arriving, Nodoka finds an ill puppy in a forest, surrounded by three magical talking animals: Rabbirin, Penguitan, and Nyatoran. They tell her that the puppy, Princess Latte, can only be cured by defeating a nearby monster known as a "Mega Byogen" and purifying the land it has corrupted. Despite being powerless, Nodoka refuses to give up and let Latte suffer. 

Moved by her determination, Rabbirin forms a pact with Nodoka, allowing her to transform into a hero known as a Precure. Assuming the persona of "Cure Grace," the energized Nodoka fights off the Byogen and heals the earth, curing Latte.

As the Byogen and their leaders continue their attacks, Penguitan and Nyatoran also find their partners in Chiyu and Hinata, giving them the powers of "Cure Fontaine" and "Cure Sparkle" respectively. Now, it's up to the three Precure and their animal friends to stop the Byogen and protect the earth from their infections!

[Written by MAL Rewrite]