The Earth has developed a defense system against large meteorites that are on a collision course with it. This protection system is made up of the Comet Blasters based in several space stations as the 1st line of defense, using nuclear warheads launched by spaceships. The 2nd line of defense consists of the Meteor Sweepers launching from ground airbases using hypersonic planes with special missiles to deal with the resulting debris from the blasts. Mikaze is a troubled girl that is a trainee pilot for a Meteor Sweeper team that dreams of becoming a prestigious Comet Blaster pilot. Stratos 4 revolves around Mikaze's and her teammates' challenges to become real pilots, while the Earth faces the threats that come from space.

Gunma Akagi, a teenager from the countryside, frequently causes a ruckus with his turbocharged tractor, much to the chagrin of his father, aspiring politician Souichirou Akagi, who urges the family to set a good example to ensure his success. One night, while Gunma is driving his tractor on the highway with his best friend Tamotsu Oishi, the two are suddenly overtaken by a speeding car. Gunma interprets this as a challenge and tries to outpace his opponent, only to fail in a spectacular fashion. The defeat sparks a fire within him, and Gunma becomes determined to win against this mysterious foe at all costs. Soon after, he leaves the peaceful countryside behind and moves to the bustling city, aiming to become the next Formula One star! [Written by MAL Rewrite]

Mink is no ordinary teenage girl, being half-human and half-dragon. Her father had fallen in love with a red dragon he intended to kill, and instead of slaying the dragon, he married her. Their union gave birth to Mink, who inherited horns, a tail, retractable wings, and incredible strength—characteristics which signify her dragon half nature. Mink spends her days accompanied by her friend Pia, a dwarf girl with overprotective parents, and her best friend Lufa, an elf with great healing powers but impressively bad magic. The three find themselves mooning over the dreamy and charming dragonslayer, Dick Saucer. But in a sudden, absurd turn of events, Mink gets closer than ever to the object of her fantasies, only to realize that her love may never be reciprocated because of her dragon heritage. Thus, the trio sets out on a quest to find a potion that will make Mink fully human. They may unwittingly make enemies, but they are sure to have one heck of a good time. [Written by MAL Rewrite]

Sixteen years after its destruction by a meteor, Graviton City has been rebuilt into a futuristic metropolis. However, this is of little concern to superpowered high school student Eiko Magami, who only cares about her best friend Shiiko Kotobuki and arriving at school on time. Unfortunately, the incredibly intelligent Biko Daitokuji intends to befriend Shiiko, taking Eiko's place as the Shiiko's best friend using any means she can. Biko decides that, to accomplish this, she must defeat Eiko in combat. In order to overcome her super strength and speed, Biko creates a mecha and challenges Eiko in front of their school gate. As the two commence their battle, an extremely large spaceship hovers over Earth, searching for something left behind. [Written by MAL Rewrite]