In this new season, we will discover the backstory of Tanmoki and who will learn through his memories who was his ancestor Rakugetsu. (Source: ANN)

Sena is like any other shy kid starting high school; he's just trying to survive. Constantly bullied, he's accustomed to running away. Surviving high school is about to become a lot more difficult after Hiruma, captain of the school's American football team, witnesses Sena's incredible agility and speed during an escape from some bullies. Hiruma schemes to make Sena the running back of his school team, The Devil Bats, hoping that it will turn around the squad's fortunes from being the laughingstock of Japan's high school leagues, to title contender. To protect his precious star player from rivaling recruiters, he enlists Sena as "team secretary," giving him a visored helmet and the nickname "Eyeshield 21" to hide his identity. The Devilbats will look to make their way to the Christmas Bowl, an annual tournament attended by the best football teams in Japan, with "Eyeshield 21" leading the way. Will they be able to win the Christmas Bowl? Will Sena be able to transform from a timid, undersized freshman to an all-star player? Put on your pads and helmet to find out!

In the heart of Italy, the Social Welfare Agency rescues young girls from hospital beds and gives them a second chance at life using the latest in cybernetic advancements. With their artificially enhanced bodies, the girls are brainwashed and trained as assassins to carry out the dirty work of the Italian Government. Despite all the modifications, they are still just children at heart, struggling for recognition from those they love, even knowing the love they feel is manufactured. This tragic tale unfolds as these girls grapple with their emotions in an agency that treats them as nothing but ruthless killers. [Written by MAL Rewrite]

Those who receive the Revelation of Babel must overcome many battles and trials. By grasping the hand of their special partner, these "Hand Shakers" transport themselves to the realm of Ziggurat, an alternate dimension where time no longer exists. Each pair of Hand Shakers must battle it out for the right to meet with God, who will reward them by granting them a single wish. Tazuna Takatsuki, a high school student with a penchant for fixing things, is one of these Hand Shakers. After receiving a request for repairs from Professor Makihara of a nearby university, Tazuna stumbles upon Koyori Akutagawa, a bedridden girl that reminds him of his deceased sister Musubu. Remembering her dying wish to never let go of her hand, Tazuna grasps Koyori's hand and awakens his power as a Hand Shaker. However, Koyori's life is directly tied to her status as a Hand Shaker, meaning if Tazuna was to ever let go of her hand she would die. With meeting God being their only hope for saving her, the duo must find a way to make their unique powers mesh together, overcome the opposing Hand Shakers, and make their wish come true. [Written by MAL Rewrite]