Gugure! Kokkuri-san is an eccentric comedy centered around the self-proclaimed doll, Kohina Ichimatsu. Her uneventful life goes from plain to absurd when she summons a fox spirit by the name of Kokkuri-san. But contrary to popular belief, he is not the omniscient, answer-granting spirit from the legend anymore. The loss of believers in modern society has rendered him powerless. Upon meeting the bizarre girl who summoned him, Kokkuri-san is shocked to discover that Kohina not only lives alone, but survives on just cup ramen! Filled with concern for the young girl, he takes it upon himself to ensure that Kohina has proper meals and lives a decent life. Thus begin Kokkuri-san's less-than-hopeful endeavors and their peculiar life together.

During the 21st century, humanity attempted to colonize Mars by sending two species which could endure the harsh environment of the planet to terraform it—algae and cockroaches. However, they did not anticipate the species' remarkable ability to adapt. Now in the 26th century, a lethal disease known as the Alien Engine Virus has arrived on Earth, and the cure is suspected to be found only on Mars. The problem is, Mars in the present is overrun by creatures known as "Terraformars," incredibly powerful and intelligent humanoid cockroaches that mutated from those originally sent to the planet. The Annex I team, consisting of a hundred men and women genetically enhanced with characteristics of powerful organisms from earth, has been sent to Mars on a mission to find the cause of the Alien Engine Virus and to help cure humanity—signalling the start of the crew's fight for survival. [Written by MAL Rewrite]

Picture drama episodes included on the DVD/Blu-ray Volumes of Seishun Buta Yarou wa Bunny Girl Senpai no Yume wo Minai.