After her parents were brutally murdered, school girl Sawa was taken into custody by Akai and Kanie, a pair of detectives assigned to her case. Corrupt and immoral, they train the girl to become a weapon, dangling the promise of vengeance in front of the hapless orphan. From celebrities and politicians to influential businessmen, Sawa is tasked with assassinating targets selected arbitrarily by her crooked overseers. She executes every mission without fail, and her distinctive weapon has become infamous among the city's police officers. Physically abused by Akai, who is no more righteous than her victims, Sawa begins to dream of a life unhindered by the shadow of her "guardians." One day, Sawa meets Oburi, a fellow orphan and vigilante. They quickly form a bond born of desperation and disgruntlement at the unjust world, envisioning a future free from the stain of murder.

It was a successful science experiment gone horribly wrong. When a team of scientists discovers the DNA of the ancient Pokémon Mew, they harnessed the potential within it in an attempt to create the ultimate living weapon. With advanced cloning techniques and resources provided to them by Team Rocket crime syndicate leader Giovanni, the scientists succeed in creating the powerful psychic Pokémon, Mewtwo.

Pokemon: Mewtwo no Gyakushuu reveals the terrifying power of Mewtwo as he learns that not only was he created to be an experiment, but also to be a tool for Giovanni’s sinister dealings. Breaking free of his control, Mewtwo creates his own island fortress and reconstructs the cloning technology that gave life to him.

Under the guise of being a master Pokémon trainer, Mewtwo lures the best trainers in the world to his base. Among these trainers are Ash Ketchum, his loyal Pokémon Pikachu, and their friends Brock and Misty. United together, human and Pokémon alike, they must not only discover the hidden secret of Mewtwo's plans, but stand against his terrifying might. If they fail, Mewtwo’s vengeance will not only lead to tyranny over all the Pokemon, but also the extinction of the human race.

Middle school student Mirai Onozawa is dissatisfied with her family circumstances and, in a moment of frustration, wishes to tear everything apart. Unfortunately, these destructive thoughts seem to come true in the form of a magnitude 8.0 earthquake just a few moments later. When summer vacation begins, Mirai reluctantly takes her younger brother Yuuki to Odaiba, where a robot exhibition that he wanted to go to is being held. However, while they are in the exhibition center, the fury of a major earthquake shakes the Kanto region; helpless, both kids witness the devastating power of this natural disaster as it brings the city to its knees. In its aftermath, they stumble upon Mari Kusakabe, a motorcyclist and single mother who decides to help the young siblings. Aiming to return to their homes and reunite with their families, the group sets off on a long and hard journey through the decimated city. [Written by MAL Rewrite]

Kujo Jotaro is a normal, popular Japanese high-schooler, until he thinks that he is possessed by a spirit, and locks himself in prison. After seeing his grandfather, Joseph Joestar, and fighting Joseph's friend Muhammad Abdul, Jotaro learns that the "Spirit" is actually Star Platinum, his Stand, or fighting energy given a semi-solid form. Later, his mother gains a Stand, and becomes sick. Jotaro learns that it is because the vampire Dio Brando has been revived 100 years after his defeat to Jonathan Joestar, Jotaro's great-great-grandfather. Jotaro decides to join Joseph and Abdul in a trip to Egypt to defeat Dio once and for all.