Set in alternate history Japan in 1931 and the 64th year of the Meiji era, the Tokugawa shogunate was never abolished and Emperor Meiji was never restored to power. The anime will follow the activities of "Nue," an organization of shogunate executioners who enforce the government. The country has developed its own energy source, the "dragon vein," and has achieved a unique development in which science and the Edo period are mixed. However, behind the glamorous city, the dissident organization Kuchinawa strives to overthrow the administration, while the Nue of the Tokugawa regime, who was entrusted with its extermination, are in conflict. Sawa Yukimura, whose family was killed when she was young, continues to search for Janome, the executioner of the Nue. (Source: MAL News)

Masane Amaha and her daughter Rihoko are on the run from a government child welfare agency that wants to take Rihoko away from her mother. They are caught and Rihoko is taken away. Meanwhile, Masane is attacked by an advanced weapon that can disguise itself as a human being. When faced with the danger, a strange light emits from her wrist and she transforms into a powerful being. She destroys the weapon and consequently becomes involved in a power struggle between powerful organizations, with her at the center of their attention. Because she holds the greatest power of them all, the legendary Witchblade. (Source: AniDB)

Tanya Degurechaff is a soldier who has the appearance of an innocent young girl. But behind her cute facade lies the soul of a ruthless salaryman who challenged "Being X"—the self-proclaimed God who reincarnated the man into an industrial world of magic. By doing this, Being X hopes to prove that, if the situation were dire enough, even a non-believer like this man would pray for God's help. Opposing Being X's desires to make her suffer, Tanya enlists in the military with the hope of living a peaceful life. She manages to impress the higher-ups with her aptitude for war, swiftly rising through the ranks. However, her country soon participates in the ongoing world war, quickly crushing her dream. In an attempt to return to her calm she starts using any merciless means to obliterate her opponents. Thus begins the saga of Tanya the Evil and the Empire as they seek world domination.

Hoping for a fresh start, househusband Masaki Fujiyoshi, his spouse Hiromu, and their toddler son, Hikari, move to a new neighborhood. The couple's union was frowned upon by many due to Masaki's status as an omega—a secondary gender that allows an individual to give birth. Even for an alpha—seen as the superior secondary gender—such as Hiromu, discrimination seems to be commonplace and a hindrance to a life of domestic bliss. Fortunately, the new family is not alone. Little Hikari becomes attached to Yuuki Hirai, the Fujiyoshis' lonely college student neighbor. Despite his initial reluctance, Yuuki ends up befriending the infant. Moreover, the family can also confide in Hiromu's childhood friend and coworker Tomohiro "Matsu" Matsuo. Although everything is going well for the young couple and their child, a sudden presence from the past might pose a problem for the peaceful life they dream of.